Chen Glyco Group |
|
Dr. Chen's previous publications |
|
26. 4Saribas, A. S.; Mobasseri, A.; Pristatsky, P.; Chen, X. ; Barthelson, R.; Hakes, D.; Wang, J. Production of N -sulfated polysaccharides using yeast expressed N -deacetylase/ N -sulfotransferase-1 (NDST-1). Glycobiology , 2004 , 14, 1217-1228. [PDF]
25. Zhang, J.; Chen, X. ; Shao, J.; Liu, Z.; Kowal, P.; Lu, Y.; Wang, P. G. Synthesis of galactose-containing oligosaccharides through superbeads and superbug approaches; substrate recognition along different biosynthetic pathways. Meth. Enzymol. 2003, 362, 106-124. [PDF] 24. Zhang, J.; Kowal, P.; Chen, X.; Wang, P. G. Large-scale synthesis of globotriose derivatives through recombinant E. coli. Org. Biomol. Chem. 2003, 1, 3048-3053. [PDF ] 23. Chen, X.; Wu, B.-Y.; Wang, P. G. Glucuronides in anti-cancer therapy. Curr. Med. Chem. -Anti-Cancer Agents 2003, 3, 139-150.
22. Nahalka, J.; Liu, Z.; Chen, X. ; Wang, P. G. Superbeads: immobilization in "Sweet" chemistry. Chemistry 2003, 9, 372-377.[PDF] 21. Chen, Y.-S.; Janczuk, A.; Chen, X. ; Wang, J.-Q.; Ksebati, M.; Wang, P. G. Expeditious syntheses of two carbohydrate-linked cisplatin analogs. Carbohydr. Res . 2002, 337, 1043-1046. [PDF] 20. Liu, Z.-Y.; Zhang, J.-B.; Chen, X.; Wang, P. G. Combined biosynthetic pathway for de novo production of UDP-galactose: catalyzed with multiple enzymes immobilized on agarose beads. ChemBioChem 2002, 3, 348-355. [PDF] 19. Chen, X. ; Liu, Z. Y.; Zhang, W.; Fang, J. W.; Andreana, P. R.; Wang, P. G. Large-scale synthesis of carbohydrate through biotechnology: Production of alpha-Gal epitopes by recombinant E. coli "superbug". ChemBioChem. 2002, 3, 47-53. [PDF] 18. Zhang, J.-B.; Wu, B.-Y.; Liu, Z.-Y.; Kowal, P.; Chen, X.; Shao, J.; Wang, P. G. Large-scale synthesis of carbohydrates for pharmaceutical development. Curr. Org. Chem. 2001, 5, 1169-1176. 17. Kowal, P.; Chen, X.; Wang, P. G. Microbial glycosyltransferases. In: Glycochemistry: Principles, Synthesis and Applications. (Editors: Wang, P. G., Bertozzi, C. R.), Marcel Dekker, Inc., New York, NY. 2001, pp. 625-640. 16. Chen, Y.-S.; Zhang, W.; Chen, X.; Wang, J.-Q.; Wang, P. G. alpha-Gal-conjugated anti-rhinovirus agents: chemo-enzymatic syntheses and testing of anti-Gal binding. J. Chem. Soc., Perkin Trans. 1, 2001 , 14 , 1716-1722.[PDF] 15. Chen, X.; Zhang, J.; Kowal, P.; Liu, Z.; Andreana, P. R.; Lu, Y.; Wang, P. G. Transferring a biosynthetic cycle into a productive E. coli strain: large-scale synthesis of galactosides. J. Am. Chem. Soc. 2001, 123, 8866-8867.[PDF] 14. Chen, X.; Fang, J.; Zhang, J.; Liu, Z.; Shao, J.; Kowal, P.; Andreana, P.; Wang, P. G. Sugar nucleotide bead (superbead): a versatile tool for practical synthesis of oligosaccharides. J. Am. Chem. Soc. 2001, 123 , 2081-2082. [PDF] 13. Xian, M.; Wang, K.; Chen, X. C.; Hou, Y. C.; McGill, A.; Chen, X.; Zhou, B.; Zhang, Z. Y.; Cheng, J.-P.; Wang, P. G. Inhibition of protein tyrosine phosphatases by low-molecular-weight S-nitrosothiols and S-nitrosylated human serum albumin. Biochem. Biophys. Res. Commun. 2000, 268, 310-314.[PDF] 12. Fang, J. W.; Chen, X.; Zhang, W.; Janczuk, A.; Wang, P. G. Synthesis of alpha-Gal epitope derivatives with a galactosyltransferase-epimerase fusion enzyme. Carbohydr. Res. 2000, 329 , 873-878.[PDF] 11. Chen, X.; Kowal, P.; Wang, P. G. Large-scale biosynthesis of oligosaccharides. Curr. Opin. Drug Discovery & Development 2000, 3 , 756-763. 10. Chen, X.; Zhang, W.; Wang J. Q.; Fang, J. W.; Wang, P. G. Production of alpha-Gal epitopes by combined UDP-galactose 4-epimerase and alpha1,3-galactosyltransferase recombinant whole cells. Biotech. Prog. 2000, 16 , 595-599.[PDF] 9. Chen, X.; Liu, Z. Y.; Wang, J. Q.; Fang, J. W.; Fan, H. N.; Wang, P. G. Changing the donor cofactor of alpha1,3galactosyltransferase by fusion with UDP-Gal 4-epimerase: more efficient biocatalysis for synthesis of alpha-Gal epitopes. J. Biol. Chem. 2000, 275 , 31594-31600.[PDF] 8. Zhang, W.; Xie, W. H.; Wang, J. Q.; Chen, X.; Fang, J. W.; Chen, Y. S.; Li, J.; Yu, L. B.; Chen, D. P.; Wang, P. G. Recent progress in glycochemistry and green chemistry. Curr. Org. Chem. 1999, 3, 241-267. 7. Janczuk, A.; Li, J.; Zhang, W.; Chen, X.; Chen, Y. S.; Fang, J. W.; Wang, J. Q.; Wang, P. G. alpha-Gal oligosaccharides: chemistry and potential biomedical application. Curr. Med. Chem. 1999, 6, 155-164. 6. Li, J.; Zacharek, S.; Chen, X.; Wang, J. Q.; Zhang, W.; Janczuk, A.; Wang, P. G. Bacteria targeted by human natural antibodies using alpha-Gal conjugated receptor-specific glycopolymers. Bioorgan. Med. Chem. 1999, 7, 1540-1558. [PDF] 5. Fang, J. W.; Chen, X.; Zhang, W.; Wang, J. Q.; Andreana, P.; Wang, P. G. A unique chemoenzymatic synthesis of alpha-Gal epitope derivatives containing free amino groups: efficient separation and further manipulation. J. Org. Chem. 1999, 64, 4089-4094. [PDF] 4. Wang, J. Q.; Chen, X. ; Zhang, W.; Zacharek, S.; Chen, Y. S.; Wang, P. G. Enhanced inhibition of human anti-Gal antibody binding to mammalian cells by synthetic alpha-Gal epitope polymers . J. Am. Chem. Soc. 1999, 121, 8174-8181.[PDF] 3. Chen, X.; Kowal, P.; Hamad, S.; Fan, H. N.; Wang, P. G. Cloning, expression and characterization of a UDP-galactose 4-epimerase from E. coli . Biotech. Lett. 1999, 21, 1131-1135.[PDF] 2. Chen, X.; Andreana, P. R.; Wang, P. G. Carbohydrates in transplantation. Curr. Opin. Chem. Biol. 1999, 3, 650-658.[PDF] 1. Fang, J. W.; Li, J.; Chen, X.; Zhang, Y. N.; Wang, J. Q.; Guo, Z. M.; Zhang, W.; Yu, L. B.; Brew, K.; Wang, P. G. Highly efficient chemoenzymatic synthesis of alpha-galactosyl epitopes with a recombinant alpha(1,3)-galactosyltransferase. J. Am. Chem. Soc. 1998, 120, 6635-6638. [PDF]
|